Darstellungsmethode des γ-Chlor acetessigesters

Abhängigkeit der Chlor-Isotopenseparation vom Vernetzungsgrad eines stark basischen Anionenaustauschers

K l a u s G . H e u m a n n , P a u l R o ß m a n n , A n n i S c h w a r z u n d A l f r e d W i n d f e l d e r Inst i tut f ü r Chemie der Univers i tä t R e g e n s b u r g Z . N a t u r f o r s c h . 34b, 4 0 6 4 1 1 (1979) ; e ingegangen a m 4. D e z e m b e r 1978 I s o t o p e Separat ion , Chlorine, I o n E x c h a n g e C h r o m a t o g r a p h y , Mass S p e c t r o m e t r y U s i ...

Des-γ-Carboxyprothrombin Plasma Level in Diagnosis of Hepatocellular Carcinoma in a Chinese Population Undergoing Surgery

BACKGROUND The usefulness of Des-g-carboxyprothrombin (DCP) has been indicated in areas where hepatitis C virus is prevalent. DCP has yet to be used in China. The aim of this study was to evaluate the usefulness of DCP in Chinese patients with hepatocellular carcinoma (HCC) predominantly caused by hepatitis B. MATERIAL AND METHODS 329 subjects with HCC and 371 subjects without HCC that all unde...

Des-γ-carboxyl prothrombin is associated with tumor angiogenesis in hepatocellular carcinoma.

BACKGROUND AND AIM Hepatocellular carcinoma (HCC) is a hypervascular tumor, and angiogenesis plays an important role in its development. Previously, we demonstrated that des-γ-carboxyl prothrombin (DCP) promotes both cell proliferation and migration of human umbilical vein endothelial cells (HUVECs) by inducing the autophosphorylation of kinase insert domain receptor (KDR). In the present study...

Effect of sorafenib on des-γ-carboxyprothrombin secretion by a human hepatocellular carcinoma cell line

Patients with hepatocellular carcinoma (HCC) who respond to sorafenib have been reported to exhibit an increase in the level of des-γ-carboxyprothrombin (DCP) in the blood, subsequent to the initiation of sorafenib treatment. In the present study, the levels of secretion of DCP and DCP with more γ-carboxyglutamic residues (NX-DCP) and the effects of hypoxic conditions were examined in 13 liver ...

The effect of chlor-amphenicol in human bone-marrow cultures.